Buyer Guide · 4 min read
Life Extension Super Omega-3 Plus vs NOW Foods Vitamin D-3 5,000 IU
Life Extension Super Omega-3 Plus compared with NOW Foods Vitamin D-3 5,000 IU on dose, price, reviews, and clinical fit.
These two supplements are the most-prescribed combination by integrative medicine doctors. Here's why you probably need both. Super Omega-3 Plus is omega-3 plus the mediterranean stack. Vitamin D-3 5,000 IU is the sunshine vitamin, 8 months per bottle. Both are stocked in our store and both are products we'd take ourselves — but they're built for different goals. This guide compares them on the metrics that actually matter when you're picking one.
| Spec | Super Omega-3 Plus | Vitamin D-3 5,000 IU |
|---|---|---|
| Brand | Life Extension | NOW Foods |
| Form | softgel | softgel |
| Size | 120 softgels | 240 softgels |
| Servings | 60 servings | 240 servings |
| Price | $36.99 | $14.99 |
| Per-serving cost | $0.62 | $0.06 |
| Rating | 4.5★ (3,021 reviews) | 4.8★ (50,879 reviews) |
| Collection | omega-3 | supplements |
Super Omega-3 Plus — what it is and who it's for
Wild fish oil concentrate from South Pacific anchovy, layered with krill oil, astaxanthin, sesame lignans, and olive polyphenols — Life Extension's most comprehensive omega-3 formula.
Key features:
- EPA/DHA fish oil + krill + astaxanthin
- Sesame lignans + olive polyphenols
- 120 softgels
- Non-GMO, gluten-free, USA made
Best for: anyone whose primary goal aligns with the the omega-3 + vitamin D foundation category and who values Life Extension's manufacturing approach.
Vitamin D-3 5,000 IU — what it is and who it's for
Highly absorbable liquid softgel form of vitamin D3. Supports healthy immune function and bone mineral density. As more people limit sun exposure, daily D3 supplementation has become a wellness staple.
Key features:
- 5,000 IU per softgel
- 240-count, 8-month supply
- Halal, kosher, soy-free, dairy-free
- GMP quality assured
Best for: anyone whose primary goal aligns with the the omega-3 + vitamin D foundation category and who values NOW Foods's approach to formulation.
How to pick
The simplest way to decide:
- If you value the formulation philosophy of Life Extension, go with Super Omega-3 Plus.
- If you value the formulation philosophy of NOW Foods, go with Vitamin D-3 5,000 IU.
- If the per-serving cost matters most, Vitamin D-3 5,000 IU is the more economical choice over time.
Both products are third-party tested, third-party reviewed, and stocked because they meet our practitioner team's quality bar. There is no wrong answer — just a fit question.
The verdict
Pick Super Omega-3 Plus if you want omega-3 plus the mediterranean stack. Pick Vitamin D-3 5,000 IU if you want the sunshine vitamin, 8 months per bottle. Or — if you're committed to the the omega-3 + vitamin D foundation category long-term — many of our customers end up using both, rotating depending on their needs.


