NeoCell

NeoCell was the brand that introduced bioactive collagen peptides to the US retail market in 1998 — back when "collagen" was a beauty-counter ingredient rather than a daily supplement category. Twenty-five years later, NeoCell's Super Collagen Peptides remains the bestselling collagen product on Amazon, with over 33,000 five-star reviews.

The product line is built around grass-fed bovine collagen Type 1 & 3, hydrolyzed to a peptide size optimized for absorption (~5,000 Daltons). Their Super Collagen + C tablet — collagen paired with vitamin C, the required cofactor for endogenous collagen synthesis — was the original formulation that established the category in 1998. The Joint Complex (Type II collagen + hyaluronic acid) is the product most-cited in the clinical osteoarthritis literature among consumer collagen supplements.

NeoCell is based in Newport Beach, CA, and is owned by Better Being (a wellness consumer goods holding company), but maintains independent quality control and formulation.